




Insulin-like Growth Factor 1 (IGF-1), also called somatomedin C, is a 70-amino acid polypeptide hormone that is structurally similar to insulin. It is primarily produced in the liver and has a half-life of 12-15 hours. The production of IGF-1 is stimulated by growth hormone (GH). Together, IGF-1 and GH promote nitrogen retention and an increase in protein synthesis, as well as promote normal bone and tissue growth. IGF-1 may be used to help build muscle mass, enhance physical performance, support muscle recovery, reduce recovery time after injuries, improve cognitive function, increase bone density, reduce body fat, regulate sugar levels, increase metabolism, and promote healthy aging.
IGF-1 DES is the truncated version of IGF-1, that is, it lacks the first three amino acids at the N-terminus of IGF-1. It is a natural variant that has a half-life of about 20-30 minutes and has been shown to be more potent than IGF-1. Besides the above uses, IGF-1 DES may also be used to help repair muscle and connective tissue. It is also a promising candidate for treating muscular dystrophy and neurological conditions.