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UNMASKING THE LINK: WHEN ANESTHESIA MEETS TRAUMATIC BRAIN INJURY (TBI) There is a concerning vulnerability being revealed at the intersection of general anesthesia and traumatic brain injury (TBI). One of the hallmarks of TBI is disruption in cerebral metabolism, which refers to the brain's energy production, utilization, and regulation processes. This includes glucose metabolism, oxygen consumption (cerebral metabolic rate of oxygen, or CMRO₂), lactate production, and mitochondrial function.
UNMASKING THE LINK: WHEN ANESTHESIA MEETS TRAUMATIC BRAIN INJURY (TBI) There is a concerning vulnerability being revealed at the intersection of general anesthesia and traumatic brain injury (TBI). One of the hallmarks of TBI is disruption in cerebral metabolism, which refers to the brain's energy production, utilization, and regulation processes. This includes glucose metabolism, oxygen consumption (cerebral metabolic rate of oxygen, or CMRO₂), lactate production, and mitochondrial function.
Individuals with a history of mild-to-moderate TBI now face heightened risks of accelerated neurocognitive decline and postoperative neurocognitive disorders following exposure to general anesthesia, even during non-brain surgeries. To remain vigilant and proactive, it is important to understand the risks involved when preparing for a procedure and discuss every detail of past brain injuries with the healthcare team and obtain a list of preventative measure.
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